Research

Clinical Trials

The APDA Information & Referral Center is pleased to maintain this listing of ongoing clinical trials for convenient access to basic information on research studies at various movement disorder centers in Massachusetts. Although the APDA has not individually reviewed or specifically endorsed each study posted here, each has been reviewed and approved by the Institutional Review Board at its respective medical center.

For further information on any study posted here, please utilize the specific contact information provided with the description of the actual study in which you are interested. As always, consult your physician to discuss the individual benefits and risks of each study prior to participating.

To submit trial information please correspond with Cathi Thomas RN, MS at information@apdama.org.


Clinical Trials in Massachusetts

 

Attentional Interventions to Improve Non-Motor and Motor Symptoms of Parkinson's Disease

 

Attentional Interventions to Improve Non-Motor and Motor Symptoms of Parkinson’s Disease
INSTITUTION: Boston University
CONTACT: The Vision and Cognition Group 617-353-6476
RECRUITMENT: Ongoing

 

Effectiveness of Bio-Electro Stimulation Therapy for the treatment of Motor and Non-Motor Symptoms in Parkinson's Disease - A Pilot Study

 

Effectiveness of Bio-Electro Stimulation Therapy for the treatment of Motor and Non-Motor Symptoms in Parkinson’s Disease – A Pilot Study
INSTITUTION: Boston University
CONTACT: The Brain Plasticity and Neuroimaging Laboratory, 617-638-5261 or brainex@bu.edu
RECRUITMENT: Ongoing

 

Biomarker Study

 

Biomarker Study (MICRO-PD)
INSTITUTION: Boston University Medical Center
CONTACT: Raymond C. James, RN, BS, 617-638-7745 or rcjames@bu.edu; Christine Tran, BA, 617-638-7747 or ctran214@bu.edu
RECRUITMENT: Ongoing

 

Evaluation of Motor and Cognitive Abilities Using Computer Program

 

Evaluation of Motor and Cognitive Abilities Using Computer Program
INSTITUTION: University of Massachusetts Amherst
CONTACT: (413) 461-0129 or kwaknlpgroup@gmail.com
RECRUITMENT: Ongoing

 

Evaluation of the Accordion Pill in Individuals with Fluctuating Parkinson’s Disease (Accordance Study)

 

Evaluation of the Accordion Pill in Individuals with Fluctuating Parkinson’s Disease (Accordance Study)
INSTITUTION: Boston University Medical Campus
CONTACT: Raymond C. James, RN, BS at 617-638-7745 or rcjames@bu.edu
RECRUITMENT: Ongoing

 

Evaluation of the ON-OFF Mobile Application and Four Actigraphy Devices in Subjects with Parkinson’s Disease

 

Evaluation of the ON-OFF Mobile Application and Four Actigraphy Devices in Subjects with Parkinson’s Disease
INSTITUTION: Boston University Medical Campus
CONTACT: Riley, (617) 414-2335 or phelpsr@bu.edu
RECRUITMENT: Ongoing

 

The Parkinson’s Stimulation Study (PD-STIM)

 

The Parkinson’s Stimulation Study (PD-STIM)
INSTITUTION: Harvard Medical School, Hebrew Rehabilitation Center
CONTACT: Arunima Awale or Rachel Harrison, (617) 971-5310 or brainstim@hsl.harvard.edu
RECRUITMENT: Ongoing

 

Digital Signatures in Parkinson’s Disease

 

Digital Signatures in Parkinson’s Disease
INSTITUTION: Tufts Medical Center
CONTACT: Lindsey Soll, 617-636-7606 or lsoll@tuftsmedicalcenter.org
RECRUITMENT: Ongoing

 

EMG Modules as a Novel Biomarker of Basal Ganglia Plasticity in Parkinson’s Disease

 

EMG Modules as a Novel Biomarker of Basal Ganglia Plasticity in Parkinson’s Disease
INSTITUTION: Spaulding Rehabilitation Hospital at Charlestown
CONTACT: Motion Analysis Research Volunteer Line, 617-952-6331
RECRUITMENT: Ongoing

 

Effort and Motivation Study in Persons with Parkinson’s Disease

 

Effort and Motivation Study in Persons with Parkinson’s Disease
INSTITUTION: Boston University
CONTACT: buamplab@gmail.com, or 617-358-2889
RECRUITMENT: Ongoing

 

Study on Inosine Medication for Early Parkinson’s Disease (SURE-PD3)

 

Study on Inosine Medication for Early Parkinson’s Disease (SURE-PD3)
INSTITUTION: Boston University Medical Center
CONTACT: Raymond C. James, RN, BS at 617-638-7745 or rcjames@bu.edu
RECRUITMENT: Ongoing

 

STEPP Lab Study

 

STEPP Lab Study
INSTITUTION: Boston University
CONTACT: stepplab@gmail.com
RECRUITMENT: Ongoing

 

Parkinson’s Progression Markers Initiative Study (PPMI)

 

Parkinson’s Progression Markers Initiative Study (PPMI)
INSTITUTION: Boston University Medical Center
CONTACT: Raymond C. James, RN, BS at 617-638-7745 or rcjames@bu.edu
RECRUITMENT: Ongoing

 

Study of Memory/Understanding in Parkinson’s Disease (SYNAPSE Study)

 

Study of Memory/Understanding in Parkinson’s Disease (SYNAPSE Study)
INSTITUTION: Massachusetts General Hospital
CONTACT: Grace Bwala at 617-643-0654
RECRUITMENT: Ongoing

 

Study Investigating Step Count Trackers (STEPS Study)

 

Study Investigating Step Count Trackers (STEPS Study)
INSTITUTION: Boston University
CONTACT: 617-358-6157 or email busteps@gmail.com
RECRUITMENT: Ongoing

 

Study on Movement in Individuals with Parkinson’s Disease or Essential Tremor

 

Study on Movement in Individuals with Parkinson’s Disease or Essential Tremor
INSTITUTION: Altec Inc.
CONTACT: 508-545-8235 or sroy@delsys.com
RECRUITMENT: Ongoing

 

Perception, Cognition, and Gait in Parkinson’s Disease: Attention

 

Perception, Cognition, and Gait in Parkinson’s Disease: Attention

  • Research study for people with mild to moderate Parkinson’s disease without dementia. Should have 8 or more years of education, English as native language (or proficient), and be able to travel to Boston. Testing takes about 3 hours per session for 3-4 sessions plus four weeks of in-home training on a computer. The study goals are to examine the ways that problems in vision, cognition, and attention can impair one’s ability to use information and ability to get around in the environment, and to help improve functioning. Compensation: $15/hour for sessions, free parking. Additional compensation for at-home training.

INSTITUTION: Boston University
CONTACT: Vision and Cognition group at 617-353-6476 or Ollie at ollieb@bu.edu
RECRUITMENT: Ongoing

 

Mental and Physical Exercise to Improve Non-Motor and Motor Symptoms of Parkinson’s Disease

 

Mental and Physical Exercise to Improve Non-Motor and Motor Symptoms of Parkinson’s Disease

  • The Vision and Cognition Lab at Boston University is recruiting participants with Parkinson’s disease (PD) for a clinical trial testing the efficacy of two brief interventions: 1) walking exercise; and 2) computer-based attention training. These 4-week programs are designed to improve thinking, sleep, mood and motor symptoms. They are both done at home on participants’ own schedules, with a total of 3 visits (spaced ~4 weeks apart) to our laboratory in Kenmore Square. Each visit takes approximately 4 hours.
  • Eligibility to participate includes having mild to moderate PD, being medication stable (no medication changes currently planned), and not having any other serious neurological conditions or poorly managed medical conditions. We are seeking participants who are currently not very physically active and not participating in cognitive enhancement programs.
  • Compensation: $15/hour for testing sessions (with free parking), $6/training session completed at home, with $50 bonus for completing all study procedures (total up to ~$326).

INSTITUTION: Boston University
CONTACT: Jade Wu, M.A. at 617-353-6476 or jqw@bu.edu
RECRUITMENT: Ongoing

 

Speech and Swallowing Function in PD

 

Speech and Swallowing Function in PD
INSTITUTION: Boston University
CONTACT: 617-358-1395 or stepplab@gmail.com
RECRUITMENT: Ongoing

 

Effects of Non-Invasive Neurostimulation Methods on Motor Function in Parkinson’s Disease Patients

 

Effects of Non-Invasive Neurostimulation Methods on Motor Function in Parkinson’s Disease Patients
INSTITUTION: Spaulding Rehabilitation Hospital
CONTACT: Melanie French at 617-952-6151
RECRUITMENT: Ongoing

 

Study of Motor Fluctuations in Patients with Parkinson’s Disease

 

Study of Motor Fluctuations in Patients with Parkinson’s Disease
INSTITUTION: Spaulding Rehabilitation Hospital
CONTACT: Motion Analysis Lab Research Volunteer Line at 617-952-6331
RECRUITMENT: Ongoing

 

Study Investigating Peer Mentoring to Increase Walking Activity

 

Study Investigating Peer Mentoring to Increase Walking Activity
INSTITUTION: Boston University, Center for Neurorehabilitation
CONTACT: Cristina Colon-Semenza at 617-358-7348 or csemenza@bu.edu
RECRUITMENT: Complete

 

Study on Inhalable Parkinson’s Medication

 

Study on Inhalable Parkinson’s Medication
INSTITUTION: Boston University Medical Center
CONTACT: Raymond C. James, RN, BS at 617-638-7745 or rcjames@bu.edu
RECRUITMENT: Complete

 

Social Self-Management of Parkinson’s Disease

 

Social Self-Management of Parkinson’s Disease
INSTITUTION: Tufts University and Boston University Medical Center
CONTACT: 617-638-7737
RECRUITMENT: Complete

 

Steady-PD III Trial

 

Steady-PD III Trial
INSTITUTION: Boston University Medical Center
CONTACT: Raymond C. James, RN, BS at 617-638-7745 or rcjames@bu.edu
RECRUITMENT: Complete

 

Study on Potential Benefits of Choral Singing in Parkinson’s Disease

 

Study on Potential Benefits of Choral Singing in Parkinson’s Disease
INSTITUTION: University of Massachusetts Amherst
CONTACT: Kelly Richardson at (413) 545-2007 or krichardson@comdis.umass.edu
RECRUITMENT: Complete

 

Tai Chi for Enhancing Balance, Walking, and Memory in Parkinson’s Disease

 

Tai Chi for Enhancing Balance, Walking, and Memory in Parkinson’s Disease
INSTITUTION: Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and Spaulding Rehabilitation Hospital
Classes will take place at Boston Medical Center
CONTACT: Kamila Osypiuk at 617-525-8738 or kosypiuk@partners.org
RECRUITMENT: Complete

 

Psychological Treatment for Anxiety for Individuals with Parkinson’s Disease

 

Psychological Treatment for Anxiety for Individuals with Parkinson’s Disease
INSTITUTION: Boston University
CONTACT: Gretchen Reynolds, MA at 617-353-9610 or bu.clinicalresearch@gmail.com
RECRUITMENT: Complete

 

Perception, Cognition, and Gait in Parkinson’s Disease and Normal Aging: Eye Movements

 

Perception, Cognition, and Gait in Parkinson’s Disease and Normal Aging: Eye Movements
INSTITUTION: Boston University
CONTACT: Vision and Cognition group at 617-353-6476 or Veena at vdali@bu.edu
RECRUITMENT: Complete

 

 

Share this page: