2018-19 Funded Research Research & Impact What We Fund 2018-19 Funded ResearchFunded Research for 2018-19George C. Cotzias FellowshipThe George C. Cotzias Fellowship is named in honor of the scientist who had a critical role in developing Levodopa as a treatment for Parkinson’ disease and is awarded with the purpose of encouraging young Neurologists to follow in his footsteps. This fellowship is a $240,000 grant awarded over a three year period.Aasef G. Shaikh, MD, PhDCleveland VA Medical Center, University Hospitals Cleveland, and Case Western Reserve University, Cleveland, Ohio The influence of basal ganglia, thalamus, and cerebellum network on discordant visual input induced gait disorder in Parkinson’s disease (PD)Vivek K. Unni, MD, PhDOregon Health & Science University, Portland, Oregon Molecular mechanisms of Lewy body pathology-associated cell death in Parkinson’s diseasePost-Doctoral FellowshipsThis fellowship is awarded to post-doctoral scientists whose research holds promise to provide new insights into the pathophysiology, etiology and treatment of Parkinson’s disease. This is a fellowship of $35,000 per year for one year.Daniel Joyce, PhDStanford University, Stanford, California Pupil-based biomarkers of Parkinson’s disease (PD)Giulietta Riboldi, MDNYU Langone Health, New York, New York Role of GBA mutation in the pathogenesis of Parkinson’s disease (PD)Research GrantsThis grant is awarded to investigators affiliated with and performing Parkinson’s disease research at major academic institutions, whose research holds promise to provide new insights into the pathophysiology, etiology and treatment of Parkinson’s disease. This is a grant of $50,000 per year for one year and is renewable.Tim Bartels, PhDBrigham and Women’s Hospital and Dementia Research Centre, University College London Alpha-Synuclein (αsyn) related lipid pathology in Parkinson’s Disease (PD)Christopher Bishop, PhDBinghamton University, Binghamton, New York Targeting the pedunculopontine tegmental nucleus to optimize treatment of Parkinson’s disease (PD)Shu G. Chen, PhDCase Western Reserve University, Cleveland, Ohio Novel knock-in models linking Rab phosphorylation to neurodegeneration in Parkinson’s disease (PD)Elizabeth Disbrow, PhDLouisiana State University Health Sciences Center, Shreveport, Louisiana Diversity in Biomarker DiscoveryYuanfang Guan, PhDUniversity of Michigan, Ann Arbor, Michigan Digital Biomarkers for Monitoring Parkinson’s Disease (PD)Mallory Hacker, PhDVanderbilt University Medical Center, Nashville, Tennessee Investigating Long-Term Clinical Outcomes of Subthalamic Nucleus Deep Brain Stimulation (DBS) in Early Stage Parkinson’s Disease (PD)Magdalena Ivanova, PhDUniversity of Michigan, Ann Arbor, Michigan Biochemical and structural studies of α-synuclein (αsyn) fibrils derived from brain tissues with Parkinson’s disease (PD) and Dementia with Lewy bodies (LB) with Alzheimer’s diseaseCameron Jeter, PhDThe University of Texas Health Science Center at Houston, Houston, Texas Protective role of the oral microbiome in Parkinson’s diseaseEunsung Junn, PhDRutgers, The State University of New Jersey, Piscataway, New Jersey In vivo identification of microRNAs associated with alpha-Synuclein (αsyn) mRNARoberta Marongiu, PhDWeill Cornell Medicine, New York, New York Menopause as an important transition state in the susceptibility to Parkinson’s disease (PD)Talene Yacoubian, MD, PhDUniversity of Alabama at Birmingham, School of Medicine, Birmingham, Alabama Rab27b as a potential regulator of alpha-synuclein spread (αsyn)2018 APDA-PF Summer Student FellowshipsThis fellowship offers undergraduate and medical students $4,000 each in funding for Parkinson’s disease research projects to be conducted in a ten-week period over the summer. The 2018 funding is a collaboration between The American Parkinson Disease Association and the Parkinson’s Foundation (PF) to support research that will help solve, treat and end Parkinson’s disease.Nadia AnabtawiMentor: Laura Volpicelli-Daley, Ph.D. University of Alabama at Birmingham Characterizing the Neuronal Internalization and Spreading of Different Conformers of α-SynucleinSidhanth ChandraMentor: Andrew West, Ph.D. University of Alabama at Birmingham Investigation of α-Synuclein Propagation and Neurodegeneration in LRRK2-knock-in Mutant MiceWai-Kat ChiaMentor: Monica Driscoll, Ph.D. Rutgers University Neuronal Extrusion of Aggregates and Mitochondria from Dopaminergic NeuronsMichelle ChuMentor: Gregory Molnar, Ph.D. University of Minnesota Subthalamic Nuclei Gamma Frequency Deep Brain Stimulation for Parkinsonian Non-Human PrimatesElsa ClintonMentor: Carlos Barcia, Ph.D. Universitat Autonoma de Barcelona Diminishing microglial activation targeting Cdc42 in Parkinson’s disease: Therapeutic approach for experimental ParkinsonismYoan GanevMentor: Shubhik DebBurman, Ph.D. Lake Forest College Evaluation of Combinatorial Impact of Post-translational Modifications on α- Synuclein in a Yeast ModelEthan MarshallMentor: Luke Johnson, Ph.D. University of Minnesota Classifying Stages of Sleep using DBS Leads in place of EEGHelen MatsoffMentor: Marina Emborg, M.D., Ph.D. University of Wisconsin-Madison Mechanisms of cardiac sympathetic axonal degenerationAshley ParkMentor: Jeff Bronstein, M.D., Ph.D. University of California, Los Angeles Air Pollution, Inflammation, and Parkinson’s DiseaseDakota PeacockMentor: Daryl Wile, MD, MSc, FRCPC University of British Columbia ParkinSMART: Parkinson’s Disease Symptom Monitoring and Recording TechnologyRichard RichterMentor: Angela Roberts, Ph.D. Northwestern University Preliminary Research into Automatic Speech AnalysisDeepikaa SriramMentor: Angela Roberts, Ph.D. Northwestern University Resolving the mystery of illegal omissions: Language-Motor interactions in real time language production in Parkinson’s Disease IN THE NEWSAPDA Awards $1.7 Million in Research Grants. 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