Clinical Studies in Connecticut

Sacred Heart University Doctor of Physical Therapy Program

Do you have Parkinson’s Disease?
Consider chair yoga to improve your walking and balance!

About the study
We are looking for people with PD to participate in a research study assessing the benefits of chair yoga on physical function! Join a certified yoga instructor and physcal therapist, along with student researchers, for 1 hour yoga sessions over 8 weeks!


NEW PD RESEARCH STUDY
Gait and Cognition
Sacred Heart University Movement Analysis Lab
Contact Dr. Joshua Lander for more information
(203)-226-2366 or josh@LSHS.pro


NEW!A Phase II, double-blind, placebo-controlled study to assess the safety and efficacy of ONO-2808

Yale is excited to offer an opportunity for people diagnosed with Multiple System Atrophy to participate in a clinical trial of a new therapy which may reduce the symptoms of the disease! Potential participants must be 60-80 years old and can have MSA-P or MSA-C.

            Contact: maxine.kuang@yale.edu or by phone at 203-292-0851


NEW! Neurodegenerative Disease Study

If you are 40-90 years of age and have been diagnosed with or know someone diagnosed with REM Behavior Disorder, Lewy Body disease or early-stage Parkinson’s disease, you or they may be eligible to participate in this study. The purpose of this research study is to see how these disorders affect brain networks, perception, and cognition. Visits involve medical screening, cognitive tests, and MRI imaging.

               Contact: fredericks.lab@yale.edu or call 203-737-4630


Do you have Parkinson’s disease and symptoms of depression?
Yale University
Take part in this research to help in the discovery of new treatments for those
fighting against Parkinson’s disease.
Contact: ketaminepd@yale.edu or call or text: (475) 287-9521



Tracing the Origin and Progression of Parkinson’s Disease through the Neuro-Immune Interactome

Observational/longitudinal study hypothesizing that in a subset of cases, PD is initiated by an autoimmune process involving alpha-synuclein specific T-cell activation by gut microbiome dysbiosis, followed by neuro-immune interactions that establish the disease in the brain.

               Contact: Kara.mead@yale.edu


NEW! Cognitive Training Study in Parkinson’s Disease

To understand the potential mental and brain effects of cognitive training in Parkinson’s disease.

               Contact: cognitive@yale.edu



NEW! Augmentation in Restless Legs Syndrome

We are recruiting patients with severe and worsening restless legs syndrome who are taking dopamine agonist medications, including ropinirole (Requip), pramipexole (Mirapex), or the rotigotine patch (Neupro). We will measure levels of particular hormones, called the melanocortin hormones in patients with RLS.

               Contact: brian.koo@yale.edu


NEW! Intestinal Immunity in Neurological Disease

If you are due for a routine colonoscopy, you may be eligible for a research study trying to determine the causes of certain neurologic diseases, such as Multiple Sclerosis or Parkinson’s. Participants will undergo tissue biopsies during their routine colonoscopy and will have a blood draw. Anyone who is due for a screening colonoscopy may qualify for the study.

Contact: MSResearch@yale.edu



SPEAK OUT! is an effective program that combines education, individual, and
group voice therapy. Sacred Heart University offers this program “FREE”!
Please contact Cristina M. Pino, M.A., CCC-SLP at: pinoc5@sacredheart.edu


Measuring Synaptic Density in Parkinson’s Disease with SV2A PET Imaging

  Investigates the changes in synaptic density in individuals with PD by using PET imaging with 11C-UCB-J, a recently developed PET radiotracer that binds to the synaptic vesicle glycoprotein, 2A.

Contact: mark.dias@yale.edu

NEW! Imaging the Dopamine Transporter in Parkinson’s Disease

Use PET imaging to examine in vivo measurement of the dopamine transporter (DAT) in PD and Healthy Control subjects.

               Contact: mark.dias@yale.edu


University of Connecticut, Department of Kinesiology, Program in Physical Therapy.

Participants wanted for a research study: Improving Gait and Quality of life in people with Parkinson’s disease through enhanced gait training. Call 860-486-9555 to learn more


People with Parkinson’s disease or other forms of parkinsonism have a much higher risk of hip and other fractures. Consider joining a virtual study where you can participate entirely from the comfort of your own home. TOPAZ (Trial of Parkinson’s and Zoledronic Acid) will test if zoledronate, can prevent fractures in people with Parkinson’s disease or other forms of parkinsonism, whether or not they have osteoporosis. You could receive $100 upon enrollment and $50 pear year during the study. For more information, please visit TOPAZstudy.org, or call us directly at (415) 317-5748.