Parkinson’s Disease Clinical Trials
Clinical trials are a crucial step in discovering the causes, treatments, and a cure for Parkinson’s. Before drugs can be approved to be used in a patient population they are rigorously reviewed through the mechanism of a clinical trial.
Below is information on research studies that are taking place at various locations across the country. Although APDA has not individually reviewed or specifically endorsed each study posted here, each has been reviewed and approved by the Institutional Review Board at its respective medical center.
For further information on any study posted here, please utilize the specific contact information provided with the description of the actual study in which you are interested. As always, consult your physician to discuss the individual benefits and risks of each study prior to participating.
Webinar: Spotlight On Clinical Trials
Here is an overview of the APDA webinar on Parkinson’s clinical trials, hosted on 9.17.21, including why clinical trials are vital to Parkinson’s research and how to participate.
To increase your awareness and connect you with ongoing research and clinical trials visit:
Active Clinical Trials
Have You Been Diagnosed with Parkinson’s Disease (PD)? Do You Know or Care for Someone With PD?
The goal of the REGENERATE-PD study is to test whether a new gene therapy (AB-1005) is safe and effective for patients with PD. This therapy aims to introduce working GDNF to your brain, which promotes the survival of braincells.
Thank you for your interest in the investigational REGENERATE-PD study. Your participation in this study may help scientists and physicians better understand PD and how to improve treatment. Your participation may contribute to the medical field and may make a positive impact on the lives of people affected by PD.
For more information, please contact AskFirst@askbio.com or scan the QR code below:
https://mytomorro.ws/pd-askfirst
ClinicalTrials.gov/study/NCT06285643
Please review AskBio’s Privacy Notice at www.askbio.com/privacy
Lend Your Voice To Parkinson’s Research
If you are age 18-100 and you have a Parkinson’s Disease diagnosis, no history of stroke, brain tumor, or other neurological conditions…you may be eligible to participate!
Our Studies involve:
- Symptom questionnairesm,
- Reading and speaking,
- Hearing and cognition screenings
- Wearing a microphone and sensors
- $30/hr and travel assistance
617-358-1395
stepplab@gmail.com
111 Cummington Mall
sites.bu.edu/stepplab/
IRB Protocol #2625
PI: Dr. Cara Stepp
PERSEVERE
PERSEVERE is a national study funded by the National Institutes of Health, led by Dr. Jori Fleisher at Rush University Medical Center in Chicago, IL, which is testing an educational program for family caregivers of people with Parkinson’s Disease with cognitive impairment, Parkinson’s Disease Dementia, Dementia with Lewy Bodies, or Lewy Body Dementia. PERSEVERE will test whether a disease-specific, caregiver-centered educational intervention improves caregiver knowledge, confidence, strain, and health outcomes – and whether it helps people living with Parkinson’s Disease Dementia, Dementia with Lewy Bodies, or Lewy Body Dementia, too.
Family caregivers will receive weekly educational guidance through a 12-week curriculum with resources and activities. All participation is virtual and scheduled when it works for you. There are no in-person visits and the person with Parkinson’s Disease, Dementia with Lewy Bodies, or Lewy Body Dementia does not participate—just caregivers. Caregivers fill out online surveys and assessments at baseline and every two weeks throughout their involvement in the study, including a six-month follow-up period after the 12-week curriculum.
Interested in learning more?
Visit https://redcap.link/PERSEVERE1 to watch a video providing more information about the study and hear testimonials from prior PERSEVERE study participants.
Email persevere@rush.edu with questions.
Help spread the word!
Do you know someone who might be interested? Please share this research opportunity with your community. The PERSEVERE curriculum has been designed by and for caregivers across the caregiving journey, including those who were past caregivers.
Curious to see if you are eligible?
Complete the pre-screening survey at https://redcap.link/PERSEVERE1.
Rehabilitation of Airway Protection in Parkinson’s Disease:
Comparing In-Person and Telehealth Service Delivery Models
Are you interested in improving your swallowing and cough function? If yes, you may be eligible to participate in a research study!
WHO: Adults with Parkinson’s disease who have swallowing and cough difficulties. Ages 50 to 90.
WHAT: You will receive free evaluations and treatment of your cough and swallowing issues.
WHERE: Teachers College, Columbia University
TIME COMMITMENT: At least 5 in-person evaluations and 16 treatment visits over 15 months. Visits will be between 60-90 minutes.
Receive up to $200 for participation.
Click here for more information.
Exploring the interplay between patient activation, loneliness, and health behaviors, in people with Parkinson’s disease
This study, conducted by the School of Nursing at the University of Connecticut, is seeking individuals with Parkinson’s Disease to complete a survey investigating the relationship between patient activation, social connectedness, health behaviors, and quality of life. The survey will take approximately 15 minutes to complete, and you can conveniently access it online. Upon survey completion, you will have the opportunity to enter to win a $25 Amazon gift card.
Your participation will play a crucial role in shaping how healthcare providers support individuals with PD to lead fulfilling lives. By sharing your experiences, you can help us tailor nursing interventions and educational strategies to better meet the needs of PD patients.
Speech Accessibility Project
Share your voice with the Speech Accessibility Project!
Now recruiting individuals with Parkinson’s to help speech recognition tools
understand diverse voices, including those affected by Parkinson’s and related
neurological diagnoses, for example, MSA, PSP, CBD, post-DBS, and LBD.
All personal information safeguarded at the University of Illinois Urbana-Champaign.
Project funded by Amazon, Apple, Google, Meta, and Microsoft.
Record your speech from the comfort of your home. Mentors from LSVT Global are
ready to help you through the participation process.
Get started today! Participants can earn up to $180. Caregivers can earn up to $90,
as well.
go.illinois.edu/SAPregistration
SPARX3
Study in PD of Exercise (Dr. Daniel Corcos,PI)
Enrollment is now open.
A new Phase 3 multi-site clinical research trial from Northwestern Medicine will test if high-intensity treadmill exercise is effective in decreasing the signs of Parkinson’s disease in individuals who have not initiated medication for Parkinson’s. There are 29 sites (27 in U.S. and 2 in Canada) including Morehouse School of Medicine in Atlanta, GA, the first HBCU-based site. This study is funded by NINDS.
UC San Diego School of Medicine: Caregiver Study
UC San Diego is working on a national research project that is seeking participants caring for family members with Parkinson’s Disease, Alzheimer’s Disease, Lewy Body dementia, or any other type of dementia. This internet-based study aims to help address the stressors that come with being a caregiver and teach coping skills that may reduce that stress and/or improve emotional well-being. Study participants get access to specialized web-programs, monetary compensation, support calls and more. See flyer for more information. Contact 858-534-9479 for details and to see if you qualify.
Learn more about Clinical Trials
Progress in treating Parkinson’s disease (PD) depends on clinical trials, and the success of clinical trials depends on people like you who volunteer to enroll in a trial. Download our brochure to learn about clinical trials, what they can offer you, and how you can learn more.