FELLOWSHIPS AND RESEARCH GRANTS ANNOUNCEMENT ACADEMIC YEAR 2009 - 2010 The American Parkinson Disease Association Inc. has budgeted research funds to be awarded during the 2009-2010 and following academic years. George C. Cotzias, MD Memorial Fellowships George C. Cotzias, MD was a pathfinder in the pharmacologic exploration of brain functions and in the treatment of Parkinson’s disease with levodopa. His work stimulated much of the current interest and research on the problems of neurological movement disorders. The American Parkinson Disease Association has established the Cotzias fellowship, in honor of his memory, to stimulate neurologists to follow his leadership. The goal of the Cotzias fellowship is to assist promising young neurologists in establishing careers in research, teaching and clinical services relevant to the problems, causes, prevention, diagnosis and treatment of Parkinson’s disease and related neurological movement disorders. DeadLine 3/1/2008   Details Fellowship/Research Grant Application Roger C. Duvoisin, MD, Research Grant The Roger C. Duvoisin, MD research grants are intended to provide support funds for established scientists affiliated with research or academic institutions located within the United States and presently not working on Parkinson’s disease research. A not-for-profit institution must sponsor the applicant and the principal goal of the grant is to support new research ideas proposed by a scientist already established in the neurological field. DeadLine 3/1/2008   Details Fellowship/Research Grant Application Research Grants The APDA research grants are intended and available for a junior investigator to pursue research in Parkinson’s disease. The applicant must be affiliated with and perform the research project at an academic institution within the United States. DeadLine 3/1/2008   Details Fellowship/Research Grant Application Post-Doctoral Fellowships The APDA Postdoctoral fellowships are awarded to support post-doctoral scientists whose research training holds promise into new insights of geriatric psycology, pathophysiology, geriatric psychology, etiology and/or treatment of Parkinson’s disease. DeadLine 3/1/2008   Details Fellowship/Research Grant Application Medical Students Summer Fellowships The APDA Summer Fellowships are designed to provide a stipend to enable medical students to perform supervised laboratory or clinical research designed to clarify our understanding of Parkinson’s disease, its nature, manifestations, etiology or treatment. It is hoped this experience will stimulate a student’s interest in future research in the field of Parkinson’s disease and related disorders. DeadLine 12/31/2007   Details Fellowship/Research Grant Application Centers for Advanced Research Funding of Centers for Advanced Research is intended to strengthen and help to integrate already existing investigative teams. Advanced Centers should have at least three successful research programs, preferably NIH funded, that include significant patient-oriented research. DeadLine 3/1/2008   Details Fellowship/Research Grant Application The funding of all Fellowships, Research Grants, including the Cotzias and Duvoisin, and Advanced Centers will be limited to scientist affiliated with institutions located within the United States. All applications will be reviewed by the APDA Scientific Advisory Board and its recommendations submitted for consideration by the APDA Executive Committee. For further information please contact Dr. Paul Maestrone, DVM, Director of Scientific & Medical Affairs at 1-800-223-2732 - Ext. 119 or Michele Popadynec, RN, Assoc. Director at ext. 118 APDA Research Funding Fiscal Year 2006 - 2007 George C. Cotzias, MD Memorial Fellowships Joseph Savitt, MD, Ph.D. Johns Hopkins Hospital Baltimore, MD Conditional GDNF Receptor Knockout Mice: Exploring the Role of GDNF in Dopaminergic Cell Development and Survival   Bradley Miller, MD, Ph.D. University of Virginia Charlottesville, VA Distribution and Metabolic Consequences of Mitochondrial DNA Deletions in Substantia Nigra and Cultured Cells   Talene Yacoubian, MD, Ph.D. The University of Alabama Birmingham, AL Role of 14-3-3 Proteins in Alpha Synuclein Induced Neurotoxicity   Roger C. Duvoisin, MD, Research Grant Andrei Alexandrescu, Ph.D. University of Connecticut Storrs, CT Stability and Solvent Accessibility of Alpha-Synuclein Fibrils by NMR Hydrogen Exchange   James L. Roberts, MD, PhD University of Texas HSC San Antonio, TX Molecular& Cellular Mechanisms of Estrogen Midiated Neuroprotection of Mesencephalic Dopamanergic Neurons   Jeffry Stock, Ph.D. Princeton University Princeton, NJ Protein Phosphatase 2A Methylation as a Therapeutic Target for Parkinson’s Disease   Research Grants Ray Dorsey, MD University of Rochester Rochester, NY A Guide to Improving the Impact of Parkinson Disease Research   Changwei Liu, Ph.D. University of Colorado at Denver Aurora, CO Studying of the Role of the CHIP/Hsp70 E3 Ligase in Mediating the Ubiquitination of Serine 129 Phosphorylated Alpha-Synuclein   Zhicheng Lin, Ph.D. The McLean Hospital Corporation Belmont, MA Genetic Variation in Human Alpha-Synuclein Expression   Wenbo Zhou, Ph.D. University of Colorado Health Sci. Ctr. Denver, CO Testing Drugs that Upregulate DJ-1 in Mouse Models of Parkinson’s Disease   Sreeganga Chandra, Ph.D. Yale University New Haven, CT Delineating the Physiological Functions of Synucleins   Andrea Giuffrida, Ph.D. University of Texas Health Science Center San Antonio, TX Neuroprotective Role of Cannabinoids in Parkinson’s Disease   Fu-Ming Zhou, Ph.D. University of Tennessee Memphis, TN An Ultra-Short Dopamine Pathway: Implications for Parkinson’s Disease   Jin Xu, Ph.D. Caritas St. Elizabeth’s Medical Ctr. Boston, MA Functional Interplay Between DJ-1 and PGC-la   Sylvain Dore, Ph.D. Johns Hopkins University School of Med. Baltimore, MD PGE2 EP1 Receptor Role in Parkinsonism   Matthew LaVoie, Ph.D. Brigham and Women’s Hospital Boston, MA Dissecting the anti-Apoptotic Function of Parkin and the Impact of PD-Linked Parkin Mutations   Lawrence Kromer, Ph.D. Georgetown University Washington, DC Role of Ephrins and Eph Receptors in Regulating Striatal Reinnervation by Dopaminergic Grafts   Andreas Kottmann, Ph.D. Columbia University New York, NY On the Function of the Secreted Cell-Signaling Glycoprotein Sonic Hedgehog (Shh) Expressed by Mesencephalic Dopaminergic Neurons in the Postnatal Brain   Steven Johnson, MD, Ph.D. Portland VA Research Foundation Portland, OR Redox Regulation of NMDA Currents in Midbrain Dopamine Neurons   Syed Iman, Ph.D. University of Texas Health Science Center San Antonio, TX Evaluation of Stress-induced Tyrosine Kinase, c-Abl, as a Novel Therapeutic Target for Parkinson’s Disease   Ming Guo, MD, Ph.D. Brain Research Institute at UCLA Los Angeles, CA Characterization of the Function of a PINK 1 Binding Protein   Matthew Goldberg, Ph.D. UT Southwestern Medical Center Dallas, TX Parkin, DJ-1 and Glutathione Peroxidase-deficient Mouse Models of PD   Baoji Xu, Ph.D. Georgetown University Washington, DC Chronic Deprivation of TrkB Signaling Leads to Progressive and Selective Nigrostriatal Dopaminergic Degeneration   Wanli Smith, MD, Ph.D. Johns Hopkins University School of Med. Baltimore, MD Cytoplasmic LRRK2 Inclusion and Ubiquitination   Sarah Berman, MD, Ph.D. University of Pittsburgh Pittsburgh, PA Exploration of Mitochondrial Dynamics in Models of Parkinson’s Disease   Asa Abeliovich, MD, Ph.D. Columbia University New York, NY Novel Therapeutics for PD     Cyrus Zabetian, MD, MS Seattle Institute for Biomedical & ClinicalResearch Seattle, WA Fine-mapping of a Chromosome 17q21 Region Associated with Parkinson’s Disease   Nigel Maidment, Ph.D. UCLA Los Angeles, CA Is VMAT Over-Expression Neuroprotective in Mammalian Alpha-Synuclein Models of PD   Stephanie White, Ph.D. University of California Los Angeles, CA Birdsong as a Model System for Parkinson’s Disease   Paul Shaw, Ph.D. Washington University St. Louis, MO Evaluating Protective Effects of Curcum in Synuclein Pathology   Lidia Serova, Ph.D. New York Medical College Valhalla, NY Mechanism of Interaction Between Nicotine and Estradiol as Related to Tetrahydrobiopterin in Animal Model of Parkinson’s Disease   Stephan Witt, Ph.D. Louisiana State University Health Sci. Ctr. Shreveport, LA Determining Why Phosphorylation of Alpha-Synuclein at Serine 129 Causes Toxicity   Jay Schneider, Ph.D. Thomas Jefferson University Philadelphia, PA Functional Significance of ALDH1 in Ventral Mesencephalic Dopamine Neurons   Owen Ross, Ph.D. Mayo Clinic Jacksonville Jacksonville, FL Dysregulation of A-Synuclein Gene Expression in Parkinson’s Disease   Janis O’Donnell, Ph.D. University of Alabama Tuscaloosa, AL In Vivo Analysis of the Role of 14-3-3 Zeta and Over-expression in Neurodegeneration in a Drosophilia PD Model   Anthony Nicholas, MD, Ph.D. The University of Alabama Birmingham, AL Post-Translational Modifications of Histones in Levodopa-Induced Dyskinesia   Guy Caldwell, Ph.D. The University of Alabama Tuscaloosa, AL Identification and Functional Validation of Neuroprotective Genes Associated with Parkinson’s Disease   Post-Doctoral Fellowships Julie Tetzlaff, Ph.D. Massachusetts General Hospital Boston, MA Therapeutic Reduction in Oligomeric Alpha-Synuclein Species   Michael Burack, MD, PhD University of Rochester Rochester, NY The Impact of Dopa-Induced Dyskinesia on Voluntary Motor Control in Patiens with Idiopathic Parkinson Disease     Allison Wright Willis, MD Washington University St. Louis, MO Environment Heavy Metal Exposure and the Risk of PD: A Community Health Study Using Geographical Information Systems   Joanne Clark, PhD Beth Israel Deaconess Medical Center Boston, MA Activation of PGC1a by P38MAPK; Potential Interference by A-synuclein   Clement Gautier, Ph.D. Brigham and Women Hospital Boston, MA Investigation of Mitochondrial Functions in PINK 1 Knock Out Mice   Melissa Geddie, Ph.D. Whitehead Institute for Biomedical Research Cambridge, MA Metal Ion Transport in Parkinson’s Disease   Keiichi Inoue, Ph.D. Columbia University New York, NY Novel Animal Models of PD   Nikolaus McFarland, MD, Ph.D. Massachusetts General Hospital Boston, MA Alpha-Synuclein Phosphorylation and Toxicity in a Rat Model of Parkinson’s   Shaji Theodore, Ph.D. The University of Alabama Birmingham, AL A Novel Mode of Microglial Activation in a Mouse Model of Parkinson’s Disease   Harrison Walker, MD The University of Alabama Birmingham, AL Clinical and Electrophysiological Investigation of Bilateral Effects of Unilateral Subthalamic Nucleus Deep Brain Stimulation   Shilpa Iyer, Ph.D. University of Virginia Charlottesville, VA In Vitro Characterization of Mechanisms of Mitochondrial DNA Homoplasmy   Medical Students Summer Fellowships David Pearce John Hopkins School of Medicine   Jennifer O'Malley Univ. of Cincinnati School of Medicine   Sara Hardy Cleveland Clinic Foundation   Centers for Advanced Research The University of Chicago Chicago, IL Boston University School of Medicine Marie St. Hilaire, MD Boston, MA   Emory University School of Medicine Mahlon DeLong, MD Atlanta, GA University of Virginia Medical Center Frederick G. Wooten, MD Charlottesville, VA   University of Alabama David Standaet, MD Birmingham, AL Robert Wood Johnson Medical School Jacob Sage, MD New Brunswick, NJ   UCLA School of Medicine Marie Francois Chessiet, MD, PhD Los Angeles, CA Washington University Medical Center Joel Perlmutter, MD St. Louis, MO   University of Pittsburgh J. Timothy Greenamyre, MD, PhD Pittsburgh, PA                © American Parkinson Disease Association, 2003. All RIghts Reserved.