3/7/14 - New research shows that ultra-high-field magnetic resonance imaging (MRI) provides detailed views of a brain area implicated in Parkinson's disease, possibly leading to earlier detection of a condition that affects millions worldwide. The results of this research are published online in the journal Radiology.
3/7/14 - Diagnosis of Parkinson's disease is not easy or straightforward: it can often be hard to distinguish from other diseases. Currently, clinicians have to rely on medical history and neurological examination, as there are no reliable radiologic techniques to aid in diagnosis.
3/6/14 - International Stem Cell Corporation, a California-based biotechnology company developing novel stem cell-based therapies and biomedical products, today announced positive data from the first interim analysis of the ongoing IND-enabling pharmacology/toxicology primate study being conducted under the supervision of Professor D. Eugene Redmond Jr. MD, of Yale University Medical School.
3/4/14 - Constipation can be another uncomfortable problem for patients with Parkinson's disease that standard treatment won't relieve, researchers say. "Constipation in Parkinson's is very prevalent," said Dr. John C.
3/4/14 - Endocrine disrupters are not the only worrying chemicals that ordinary consumers are exposed to in everyday life. Also nanoparticles of silver, found in e.g. dietary supplements, cosmetics and food packaging, now worry scientists. A new study from the University of Southern Denmark shows that nano-silver can penetrate our cells and cause damage.
3/4/14 - For people whose hands shake uncontrollably due to a medical condition, just eating can be a frustrating and embarrassing ordeal - enough to keep them from sharing a meal with others.
3/4/14 - After a natural disaster like a big fire, countless helpers work together to get rid of debris, to build temporary shelters and to provide food for people in need. When a cell is exposed to dangerous environmental conditions such as high temperatures or toxic substances, a quite similar process is initiated: the cellular stress response, also called heat shock response.
3/2/14 - Despite widespread use of a single term, Alzheimer's disease is actually a diverse collection of diseases, symptoms and pathological changes. What's happening in the brain often varies widely from patient to patient, and a trigger for one person may be harmless in another.
2/24/14 - An ancient chemical, present for billions of years, appears to have helped proteins function properly since time immemorial.Proteins are the body's workhorses, and like horses they often work in teams. There exists a modern day team of multiple chaperone proteins that help other proteins fold into the complex 3D shapes they must achieve to function.
2/21/14 - Geneticists from Trinity College Dublin interested in 'reverse engineering' the nervous system have made an important discovery with wider implications for repairing missing or broken links.
2/20/14 - The U.S. Food and Drug Administration has approved Northera capsules (droxidopa) for the treatment of neurogenic orthostatic hypotension (NOH). NOH is a rare, chronic and often debilitating drop in blood pressure upon standing that is associated with Parkinson's disease, multiple-system atrophy, and pure autonomic failure.
2/14/14 - Scientists report that they have developed a novel compound that appears to protect mice against developing movement problems associated with Parkinson's disease (PD). The research, which could one day in the future translate into a therapy that could halt the progression of PD and thereby prevent the symptoms of the disease, appears in ACS' Journal of Medicinal Chemistry.
2/14/14 - Surgical implants are widely used in modern medicine but their effectiveness is often compromised by how our bodies react to them. Now, scientists at the University of Cambridge have discovered that implant stiffness is a major cause of this so-called foreign body reaction.This is the first time that stiffness of implant materials has been shown to be involved in foreign body reactions.
2/11/14 - Scientists from the School of Medicine at The University of Texas Health Science Center at San Antonio have found a clue as to why muscles weaken with age. In a study published in The Journal of Neuroscience, they report the first evidence that "set points" in the nervous system are not inalterably determined during development but instead can be reset with age.
2/7/14 - A new study, published in the journal Applied Materials & Interfaces, has found a new method for growing human embryonic stem cells, that doesn't rely on supporting human or animal cells.Traditionally, these stem cells are cultivated with the help of proteins from animals, which rules out use in the treatment of humans.
2/6/14 - Previously, stem cells have been cultivated using animal proteins or by growing them from other human cells. Both methods come with associated problems. But, according to a study published in the journal Applied Materials & Interfaces, researchers have now identified a new method for cultivating stem cells.
2/5/14 - University of Queensland researchers have made a surprise discovery about how the brain plans movement that may lead to more targeted treatments for patients with Parkinson's disease.
2/4/14 - According to the Parkinson's disease foundation, more than 1 million Americans have the disease. Now, new research suggests that exposure to pesticides may increase the risk of the disease and that individuals with specific gene variants may be more susceptible. This is according to a study recently published in the journal Neurology.
2/3/14 - Neurodegenerative diseases like Parkinson's disease involve the death of thousands of neurons in the brain. Nerve growth factors produced by the body, such as GDNF, promote the survival of the neurons; however, clinical tests with GDNF have not yielded in any clear improvements.
1/31/14 - Neurostemcellrepair (European stem cell consortium for neural cell replacement, reprogramming and functional brain repair) is formed to create a world-leading consortium that aims at taking human stem cells through the final steps toward clinical application in cell replacement therapy.
1/30/14 - A new study shows that, when properly manipulated, a population of support cells found in the brain called astrocytes could provide a new and promising approach to treat Parkinson's disease.
1/28/14 - A new method allows for large-scale generation of human embryonic stem cells of high clinical quality. It also allows for production of such cells without destroying any human embryos. The discovery is a big step forward for stem cell research and for the high hopes for replacing damaged cells and thereby curing serious illnesses such as diabetes and Parkinson's disease.
1/28/14 - Scientists at Johns Hopkins report they have figured out a key step in how "free" calcium - the kind not contained in bones - is managed in the body, a finding that could aid in the development of new treatments for a variety of neurological disorders that include Parkinson's disease.
1/25/14 - Long-term treatment that involves electrically stimulating the spinal cord has improved symptoms of Parkinson's disease in rats. Publishing the results of their study in the journal Scientific Reports, researchers from Duke Medicine are hopeful their findings could help human Parkinson's patients.The team, led by Dr.
1/24/14 - How aging affects communication between neurons is not well understood, a gap that makes it more difficult to treat a range of disorders, including Alzheimer's and Parkinson's disease.